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32
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Course No.
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Course Title
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No. of Units
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Pre-requisites
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Th.
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Pr.
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Credit
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Chem 426
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Bioinorganic Chemistry
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2
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-
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2
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Chem 322
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Course objective:
This
course is aimed to give the students a chemical background in the role
of the elements and their complexes in living organisms. Role of enzymes
and coenzymes, macrocyclic chelating ligands. Importance of
microelements to living system, medicinal chemistry.
Course description:
This
course includes an introduction to bioinorganic chemistry and its
relation with other branches of chemistry as well as of other sciences.
Role and function of inorganic elements in biological system.
Macrocyclic chelate ligands. Nucleobases, neucleotides, and nucleic acid
as ligands, dealing with models, corrin, porphyrin,cobalamines,
cytochromes, haemoglobin, oxygen carriers, ferrodoxins, redox reactions,
blue copper proteins, photosynthesis, vitamin B, inhibition and
poisoning, essential biological microelements, and medicinal chemistry.
Main text books
§ Bioinorganic
Chemistry: Inorganic Elements in the Chemistry of Life: an
introduction, W. Kaim and B. Schwederski, 1994 John Wiley.
Subsidiary books:
§ Bioinorganic Chemistry, I. Bertini, H. B. Gray, S. J. Lippard and J. S. Valentine,1994, Mill Valley.
§ Principles of Bioinorganic Chemistry, S. J. Lippard & J. M. Berg, 1994, Mill Valley.
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